Printed in the U.S.A. POMC IN RHESUS ANTERIOR PITUITARY AND PLASMA: EVIDENCE OF N-ACETYLATED B-ENDORPHIN AND a-MSH
نویسندگان
چکیده
Immunocytochemical staining demonstrated N-acetylatedB-endorphin (N-AcB-End) and a -MSH in a few corticotrophs. RIA's of crude anterior pituitary extract and molecular sieving chromatography demonstrates that the major portion is B-End sized with a significant proportion being N-acetylated and an a-MSH peak. Molecular sieving chromatography of extracted plasma demonstrated a similar pattern to that seen in the anterior pituitary. These data suggest that rhesus monkey processes POMC differently than rat or man.
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